N/A
N=77
Accelerated Recovery Pathway for Discharge After Surgery in Patients With Pancreatic Cancer
Pancreatic Carcinoma
Bottom Line
View on ClinicalTrials.gov: NCT02517268 ↗Enrolled (actual)
77
Serious AEs
1.3%
Results posted
Dec 2019
Primary outcome: Primary: Percentage of Patients Discharged by Post-operative Day 5 — 5; 28 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Pancreaticoduodenectomy (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
- Primary completion
- Jan 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Patients Discharged by Post-operative Day 5 |
5; 28 | — |
| SECONDARY Post-operative Median Length of Stay |
6; 5 | — |
| SECONDARY Cost |
155,542; 139,735 | — |
| SECONDARY Readmission Rate |
4; 3 | — |
| SECONDARY Incidence of Post-operative Complications (DGE, Anastomotic Leaks, Intra-abdominal Abscesses, Wound Infection, UTI, Respiratory Compromise, Renal Failure, Etc.) |
13; 5; 0; 0; 1; 1 | — |
Summary
This randomized clinical trial studies accelerated recovery pathway for discharge after surgery in patients with pancreatic cancer. A standardized accelerated recovery pathway may improve outcomes after surgery following complex abdominal operations resulting in a shorter length of stay in patients with pancreatic cancer. It may also help patients to mobilize more quickly and return to the home setting, decrease hospital-acquired infectious complications, and increase potential cost savings. It is not yet known whether an accelerated recovery pathway is better than a standard recovery pathway for discharge following surgery in patients with pancreatic cancer.
Eligibility Criteria
Inclusion Criteria
- Pancreaticoduodenectomy
- Firm gland texture
- Subjects able to provide informed consent
Exclusion Criteria
- Preoperative factors:
- Congestive heart failure (CHF)
- End stage renal disease (ESRD)
- Chronic obstructive pulmonary disease (COPD)
- Pregnancy
- Albumin 1 liter
- Failure to extubate at the conclusion of the case
- Operative time > 8 hours
- Need for vascular resection/reconstruction
Data sourced from ClinicalTrials.gov (NCT02517268). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.