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N/A N=29 Randomized Single-blind Treatment

DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation

Refractive Error

Enrolled (actual)
29
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcome: Primary: Tear Film Evaporation Rate — 120.88; 105.63 gm^-2 h

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Delefilcon A contact lenses (Device); Narafilcon A contact lenses (Device); Somofilcon A contact lenses (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Apr 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Tear Film Evaporation Rate
120.88; 105.63

Summary

The purpose of this study is to evaluate the tear film evaporation of symptomatic soft contact lens wearers in the absence of contact lens wear and after at least 8 hours of contact lens wear.

Eligibility Criteria

Inclusion Criteria

  • Sign an informed consent document;
  • Adapted, current soft contact lens wearer;
  • Symptoms of contact lens discomfort as defined by the Symptomatology (Eligibility) Questionnaire;
  • Can be successfully fitted with study lenses;
  • Willing to wear lenses for a minimum of 8 hours prior to each study visit;
  • Willing to discontinue artificial tears and rewetting drops usage on the days of study visits;
  • Other protocol-specified inclusion criteria may apply.

Exclusion Criteria

  • Ocular anterior segment infection, inflammation, abnormality, or active disease that would contraindicate contact lens wear;
  • Use of systemic or ocular medications for which contact lens wear could be contraindicated as determined by the investigator;
  • Monocular (only 1 eye with functional vision) or fit with only one lens;
  • History of herpetic keratitis, ocular surgery, or irregular cornea;
  • Known pregnancy and lactation;
  • Other protocol-specified exclusion criteria may apply.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02517567). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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