Phase 4
Completed N=109
Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients
Surgical Conditions
Source: ClinicalTrials.gov NCT02553629 ↗
Enrolled (actual)
109
Serious AEs
0.0%
Results posted
Feb 2017
Primary outcomePrimary: Surgical Rating — 4.2; 4.8 units on a scale — p=0.001
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
This is a randomized control trial (RCT) that studies the surgical conditions during moderate and deep neuromuscular blockade in 100 morbidly obese patients receiving elective laparoscopic surgery for bariatric surgery.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Surgical Rating |
4.2; 4.8 | 0.001 sig |
| SECONDARY Extubation |
3; 3 | >0.05 |
| SECONDARY Pain |
4.4; 3.9 | 0.04 sig |
| SECONDARY Respiration |
12.7; 12.6 | >0.05 |
| SECONDARY Mean Arterial Blood Pressure |
98; 101 | >0.05 |
Eligibility Criteria
Inclusion Criteria
- ASA I-III
- BMI > 34 kg/m2
- Elective bariatric surgery.
Exclusion Criteria
- Known or suspected neuromuscular disorders impairing neuromuscular function
- Allergies to muscle relaxants, anesthetics or narcotics
- A(family) history of malignant hyperthermia
- Women who are or may be pregnant or are currently breast feeding
- Renal insufficiency, as defined by serum creatinine x 2 of normal, or urine output < 0.5 ml/kg/h for at least 6 h.
Data sourced from ClinicalTrials.gov (NCT02553629). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.