Phase 4 N=70 Randomized Quadruple-blind Other

The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal Surgery

Neuromuscular Blockade

Bottom Line

View on ClinicalTrials.gov: NCT02580188 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2018

Primary outcome: Primary: Number of Participants With Increased Intra-abdominal Pressure (IAP) Alarm as > 15 mmHg — 14; 6 Participants

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: sugammadex (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Seoul National University Bundang Hospital
Primary completion: Jun 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants With Increased Intra-abdominal Pressure (IAP) Alarm as > 15 mmHg	14; 6	—

Summary

This study is a randomized, controlled, double-blinded, and parallel design study. A total 96 patients were randomized to receive a deep block or a moderate block scheduled for elective laparoscopic colorectal surgery. Investigators estimated the proportion of intra-abdominal pressure(IAP) alarm and surgical rating score.

Eligibility Criteria

Inclusion Criteria

American Society of Anesthesiologists grade 1 or 2
Scheduled for elective laparoscopic Colorectal surgery

Exclusion Criteria

Severe respiratory or cardiac disease
Severe hepatic or renal function impairment
On medications affecting neuromuscular function
Known allergy to the drugs to be used
Pregnant
Malignant hyperthernia

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02580188). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.