N/A
Completed N=88
Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus Aprepitant
Source: ClinicalTrials.gov NCT02597907 ↗Enrolled (actual)
88
Serious AEs
0.0%
Results posted
Apr 2017
Primary outcomePrimary: The Incidence of Postoperative Nausea and Vomiting — 5; 18 Participants — p=<0.05
Summary
The purpose of this study was to compare the antiemetic efficacy of aprepitant plus palonosetron versus aprepitant plus ramosetron in high risk patients undergoing laparoscopic cholecystectomy.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Incidence of Postoperative Nausea and Vomiting |
5; 18 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- Non smoking, female patients, scheduled for laparoscopic cholecystectomy
Exclusion Criteria
- Patients with gastrointestinal disorder,
- Patients with allergies to any study medication,
- Patients who had received any sedatives, opioid, steroid or antiemetics within 24 h before surgery
Data sourced from ClinicalTrials.gov (NCT02597907). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.