N/A N=15 Randomized Triple-blind Other

Topical Centella Asiatica and the Cosmetic Appearance of Stretch Marks

Stretch Marks · Striae Distensae · Cosmetic Appearance of Stretch Marks

Bottom Line

View on ClinicalTrials.gov: NCT02601105 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2021

Primary outcome: Primary: Cosmetic Outcome- Fraction Improving by at Least 1 Point Increase in Overall Appearance of Stretch Marks — 3; 5 Participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Placebo Vehicle Cream (Other); Centella Asiatica Cream (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: Female
Sponsor: University of California, Davis
Primary completion: Aug 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Cosmetic Outcome- Fraction Improving by at Least 1 Point Increase in Overall Appearance of Stretch Marks	3; 5	—
PRIMARY Stretch Mark Width/Area	0.8; 0.87	—

Summary

The purpose of this study is to clinically evaluate the efficacy, safety as well as patient satisfaction in the use of topical Centella asiatica (CA) on the cosmetic appearance of stretch marks.

Eligibility Criteria

Inclusion Criteria

English-speaking subjects over the age of 18
Subjects clinically diagnosed with stretch marks

Exclusion Criteria

History of keloid scarring
Isotretinoin use within the last 6 months
Oral prednisone use within the last 3 months
Non-ablative laser procedures to the abdomen within 1 year of study initiation
Ablative resurfacing procedures to the abdomen within 3 years of the study initiation
Pregnancy
Use of immunosuppressive drugs
Known hypersensitivity to Centella asiatica

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Data sourced from ClinicalTrials.gov (NCT02601105). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.