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N/A Completed N=60 Randomized Single-blind Basic Science

The Use of i/t Curve in Assessment of Phototherapy Effects

Nerve Disorders
Source: ClinicalTrials.gov NCT02618642 ↗
Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jan 2020
Primary outcomePrimary: Change in the Pressure Pain Threshold (PPT) — 0.0; -0.5; -1.3; -0.6 lbs — p=0.3879

Summary

Conventional electrodiagnostic examination is useful in daily physiotherapeutic practice. Nevertheless, the subjective assessment of muscle contraction and perceived current vibrations carries the risk of error and thus is a limitation of the method. Therefore, the use of the I/T curve coefficient was proposed in this study. This coefficient is the arithmetic mean of the electrical charge needed to trigger a sensory or motor reaction at different widths of the electrical pulse. PILER (Polychromatic Incoherent Low-Energy Radiation) light affects the sensory and motor excitability of the tissue. The resulting changes may depend on the colour of the filter used in the irradiations. The study aimed to: 1. To evaluate changes in neuromuscular excitability occurring after PILER irradiation using filters of different colours. 2. To evaluate the usefulness of the I/T curve coefficient in neuromuscular excitation test. 60 healthy volunteers were assigned to one of four groups irradiated with: 1 - Piler light + red filter, 2 - Piler light + blue filter, 3 - Piler light without a filter, 4 - placebo. Main Outcome Measures were plotting I/T curve coefficient for rectangular (■I/T coeff) and triangular (▲I/T coeff) pulses and the pressure pain threshold (PPT).

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in the Pressure Pain Threshold (PPT)
0.0; -0.5; -1.3; -0.6 0.3879
PRIMARY
Calculation of Sensory i/t Curve Coefficient for Rectangle (■I/T Coeff)
0.0007; 0.0008; 0.0006; 0.0001 0.4669
PRIMARY
Calculation of Sensory I/T Curve Coefficient for Triangular (▲I/T Coeff) Pulses
0.0014; 0.0018; 0.0015; 0.0018 0.9596
PRIMARY
Calculation of Motor i/t Curve Coefficient for Rectangle (■I/T Coeff)
0.0009; 0.0015; 0.0006; 0.0007 0.0110 sig
PRIMARY
Calculation of Motor I/T Curve Coefficient for Triangular (▲I/T Coeff) Pulses
0.0028; 0.0050; 0.0024; 0.0030 0.0200 sig

Eligibility Criteria

Inclusion Criteria included: informed consent, good tolerance of current pulses, completion of all phototherapy sessions, declaration of alcohol/drugs/smoking abstinence The exclusion criteria were: acute inflammatory processes and fever, the presence of pigmented moles in the irradiated area, exposure to any other physical factors, a history of upper limb trauma, and upper limb overload.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02618642). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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