N/A N=30 Randomized Double-blind Treatment

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Arthropathy of Hip · Arthropathy of Knee

Bottom Line

View on ClinicalTrials.gov: NCT02619409 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2018

Primary outcome: Primary: Duration of Sensory Block — 3.41; 2.81; 3.23; 3.12 hours

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Bupivacaine Only (Drug); EPI25 (Drug); EPI50 group (Drug); EPI75 group (Drug); EPI100 group (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Medical University of South Carolina
Primary completion: Oct 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Duration of Sensory Block	3.41; 2.81; 3.23; 3.12; 3.22	—
PRIMARY Duration of Motor Block	3.74; 3.36; 3.39; 4.06; 5.20	—

Summary

Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block. The epinephrine wash may prolong the duration of the block, and if it does, to what extent?

Eligibility Criteria

Inclusion Criteria

18 years of age or older
Patients scheduled for total hip or knee replacement

Exclusion Criteria

Patients taking anticoagulation
Infection at or near the intended needle insertion site
Patients with sacral decubitus ulcer at or near the intended needle insertion site aortic stenosis
Complex spine anatomy
ASA class greater than III
Failed SAB as determined by the staff anesthesiologist

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02619409). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.