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Phase 4 Completed N=40 Randomized Double-blind Treatment

Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.

Delayed Emergence From Anesthesia
Source: ClinicalTrials.gov NCT02631525 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Aug 2020
Primary outcomePrimary: Extubation Time — 9.5; 6.2 minutes

Summary

Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.

Outcome Measures

OutcomeResultp-value
PRIMARY
Extubation Time
9.5; 6.2

Eligibility Criteria

Inclusion Criteria

  • Female patients over 18 years old classified by the American Society of Anesthesiologists as physical status I or II, undergoing elective breast surgery with general anesthesia.

Exclusion Criteria

  • History of: illegal drug and alcohol abuse
  • Pregnancy on course or suspicion of
  • Neuromuscular disorders
  • Cerebral vascular disease
  • Dysphagia
  • Dysphonia
  • Gastroesophageal reflux disease
  • Previous larynx and/or upper gastrointestinal tract surgery
  • Allergy to any drug to be used and malignant hyperthermia.
  • Patients who develop hemodynamic instability in the surgery and need blood transfusion were excluded from the study.
  • Patients unable to swallow 20 ml of water in an upright position were also excluded.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02631525). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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