Phase 4 N=50 Randomized Triple-blind Treatment

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

Idiopathic Scoliosis · Post-operative Pain

Bottom Line

View on ClinicalTrials.gov: NCT02651324 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2025

Primary outcome: Primary: Patient Satisfaction — 2.75; 2.92; 3.31; 3.13 score on a scale

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Ketamine (Drug); Placebo (Other)
Age: Pediatric, Adult, Older Adult
Sex: All
Sponsor: Albany Medical College
Primary completion: Dec 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Patient Satisfaction	2.75; 2.92; 3.31; 3.13	—
SECONDARY Pain Score	3.17; 3.9	—
SECONDARY Opioid Use	0.577; 0.83	—
SECONDARY Length of Stay	5.46; 5.52	—

Summary

This study hypothesizes that the addition of a low-dose ketamine infusion to usual post-operative pain management will improve pain control as evidenced by an improvement in post-operative pain scores for patients undergoing spinal fusion for idiopathic scoliosis.

Eligibility Criteria

Inclusion Criteria

ASA I, II, III
Presenting for spinal fusion for idiopathic scoliosis
English-speaking and able to give assent

Exclusion Criteria

Any contraindication to ketamine
Previous spinal surgery
Opioid dependence
Chronic pain condition
Significant developmental delay
Pregnancy

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02651324). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.