N/A N=55 Diagnostic

Determination of Liver Stiffness in Chronic Liver Disease Patients by Acoustic Radiation Force Imaging (ARFI) Ultrasound

Chronic Liver Disease

Bottom Line

View on ClinicalTrials.gov: NCT02652221 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2017

Primary outcome: Primary: Agreement in Measured Liver Stiffness Between ARFI and MRE — 3.21; 2.48; 1.81; 2.0 kPa

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Acoustic Radiation Force Imaging (Device)
Age: Pediatric, Adult · 0+ yrs
Sex: All
Sponsor: Children's Hospital Medical Center, Cincinnati
Primary completion: Dec 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Agreement in Measured Liver Stiffness Between ARFI and MRE	0.61; 0.07	—

Summary

A prospective, pilot study using acoustic radiation force imaging (ARFI) ultrasound (US) to quantify liver stiffness in children and young adults with chronic liver disease. ARFI results will be compared to the current clinical standard of Magnetic Resonance Elastography (MRE) and to liver biopsy when available.

Eligibility Criteria

Inclusion Criteria

Less than 25 years old with chronic liver disease

Exclusion Criteria

Subjects without clinically ordered MRE
Subjects who cannot cooperate with performance of the short ARFI exam

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02652221). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.