N/A N=6 Other

Vestibular Rehabilitation and Otolith Dysfunction

Dizziness

Bottom Line

View on ClinicalTrials.gov: NCT02652442 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2021

Primary outcome: Primary: Change in Static Subjective Visual Vertical (SVV) — 0.69; 0.58; 0.69; 0.89 degrees — p=0.97

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Centrifugation Distance (Behavioral); Centrifugation Duration (Behavioral); Centrifugation Schedule (Behavioral)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: VA Office of Research and Development
Primary completion: Jul 2020

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Static Subjective Visual Vertical (SVV)	0.69; 0.58; 0.69; 0.89; 0.89; 0.32	0.97

Summary

Recent studies suggest that otolith dysfunction is a common finding in individuals with a history of head trauma/blast exposure and/or noise-induced hearing loss. Therefore, otolith dysfunction may be a significant health concern for the Veteran population, and determining optimal intervention strategies for otolith dysfunction is important for VA healthcare. The purpose of this project is to identify optimum stimulus parameters of a novel treatment, off-axis rotation (centrifugation) for otolith dysfunction, in healthy participants.

Eligibility Criteria

Inclusion Criteria

At least 18 years of age
Documented balance or mobility problems, or healthy control without imbalance
Otolith dysfunction or healthy control without vestibular dysfunction

Exclusion Criteria

Progressive neurological disorders and central vestibular abnormalities
Benign paroxysmal positional vertigo
Superior semicircular canal dehiscence
Middle-ear pathology with conductive hearing loss
Lower extremity joint replacement
Cognitive impairment (Mini Mental Status Exam < 24/30)
Severe depression (geriatric depression scale 10)
Severe anxiety (geriatric anxiety inventory 11/30)
Best-corrected visual acuity worse than 20/40 in the better eye

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02652442). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.