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N/A Completed N=28 Randomized Supportive Care

Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants

Hypoplastic Left Heart Syndrome · Growth Failure
Source: ClinicalTrials.gov NCT02657629 ↗
Enrolled (actual)
28
Serious AEs
11.5%
Results posted
Feb 2016
Primary outcomePrimary: Weight Gain in Grams Per Day — 24.3; 23.6 grams/day — p=0.05

Summary

The purpose of the study is to determine if a continuous feeding regimen as compared to an intermittent bolus feeding regimen leads to improved weight gain in infants with hypoplastic left heart syndrome (HLHS) after stage 1 procedures.

Outcome Measures

OutcomeResultp-value
PRIMARY
Weight Gain in Grams Per Day
24.3; 23.6 0.05

Eligibility Criteria

Inclusion Criteria

  • Subjects with HLHS/SVV who underwent stage 1 procedures (Norwood or Hybrid procedure) who were inborn or transferred into the Neonatal Intensive Care Unit at Columbia University Medical Center

Exclusion Criteria

  • Excluded subjects were those with associated major congenital malformations (e.g. congenital diaphragmatic hernia, gastroschisis) or chromosomal anomalies, and/or those who were small for gestational age at birth.
  • Subjects in whom a nasogastric tube or gastrostomy tube was not required for feeding at the time of enrollment and/or who were transferred to outside institutions for recovery after surgery.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02657629). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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