Observational Study to Evaluate Long-term Safety and Biodegradability of YVOIRE Volume s

Inclusion Criteria

• Subjects whose age is over 18 years old and under 65 years old
• Subjects whose WSRS grade is equal or greater than 2
• Subjects must be willing and able to provide written informed consent form
• Subjects who are scheduled to be treated with YVOIRE volumes for facial tissue augmentation to correct the nasolabial folds

Exclusion Criteria

• Subjects who are sensitive to hyaluronic acid or any excipients of YVOIRE volume s
• Subjects who have received permanent implantation (silicone, PAAG, PMMA, CaHA etc) on the nasolabial folds
• Subjects who have received nonpermanent aesthetic treatments, such as botulinum toxin injection or filler on the nasolabial folds within 9 months before screening
• Subjects who have received face lifting or plastic surgery on face within 9 months before screening
• Subjects who have received laser therapy on the nasolabial folds, chemical peeling or peeling on face within 3 months before the screening
• Subjects who have any skin diseases (including inflammation and skin cancer) or infectious diseases on the injection sites
• Subjects who tend to have hypertrophic scars
• Subjects with a history of streptococcal disease, severe allergy or anaphylaxis or bleeding disorders.
• Women in pregnancy or lactation