N/A
Completed N=10
Comparing the Ketogenic Effect of Coconut Oil and Different MCTs
Healthy Adults
Source: ClinicalTrials.gov NCT02679222 ↗
Enrolled (actual)
10
Serious AEs
0.0%
Results posted
Apr 2020
Primary outcomePrimary: Plasma Ketone Concentrations — 69; 294; 109; 363 µmol/L
Summary
The aim of this study is to compare the ketogenic effect of coconut oil and three MCT oils (60-40 , tricaprylin and triheptanoate) on the production of ketones in healthy adults. Each oil are evaluated individually or in combination over a 8h-period during which repeated blood sampling is performed.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Plasma Ketone Concentrations |
69; 294; 109; 363; 107; 141 | — |
| SECONDARY Plasma Acetoacetate/Beta-hydroxybutyrate Ratio |
7.7; 6.9; 7.7; 5.9; 9.5; 8.4 | — |
Eligibility Criteria
Inclusion Criteria
- Healthy adult over 18 y old.
Exclusion Criteria
- Fasting plasma glucose ≥7.0 mM (diabetics or pre-diabetics);
- Smoking
- Clinically-significant gastro-intestinal disease/conditions.
- Clinically-significant liver disease/dysfunction.
- Clinically-significant cardiac disease/conditions.
- Clinically-significant abnormal coagulation.
- Taking a medication that could affect lipid and glucose metabolism
- Hypertension
- Pregnancy or breastfeeding
- Exercising more than 3 times a week
Data sourced from ClinicalTrials.gov (NCT02679222). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.