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N/A N=39

Exploratory Study of Relationships Between Malodor and Urine Metabolomics

Nutritional and Metabolic Diseases

Enrolled (actual)
39
Serious AEs
0.0%
Results posted
Oct 2020
Primary outcome: Primary: Differences in Metabolite Concentrations in Urine Between Individuals With Malodor Issues and Age-matched Healthy Controls. — 3.4; 8.6; 0.443; 0.8 uMol/mM creatinine

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Mebo Research, Inc.
Primary completion
Aug 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Differences in Metabolite Concentrations in Urine Between Individuals With Malodor Issues and Age-matched Healthy Controls.
3.4; 8.6; 0.443; 0.8; 4.0; 3.0
SECONDARY
Correlations Between Urine Biomarkers and Frequency/Severity of Malodor Symptoms (Questionnaires)
3; 3; 0.5; 0.4; 4; 3

Summary

The purpose of this study is to identify metabolic signatures associated with malodor conditions. The investigators will perform state-of-the art metabolomics tests and bioinformatic data mining to explore if conditions leading to malodor can be screened by metabolomic profiling of urine samples.

Eligibility Criteria

Inclusion Criteria

  • 18 years or older
  • unpredictable and uncontrollable episodes of malodor
  • willing and able to ship a urine sample (in the kit provided) by an overnight courier to Edmonton, Alberta, Canada
  • good general health

Exclusion Criteria

  • serious medical conditions that require treatment
  • conditions that, in the opinion of the investigator, would prevent participation
  • under the age of 18
  • elect not to participate in the study
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02683876). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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