Phase 4
Completed N=20
Cryoanalgesia vs. Epidural in the Nuss Procedure
pectus excavatum · Funnel Chest
Source: ClinicalTrials.gov NCT02721017 ↗
Enrolled (actual)
20
Serious AEs
10.0%
Results posted
May 2021
Primary outcomePrimary: Length of Hospitalization — 3; 5 Length of Stay (Post-Operative Days)
◆ Published Evidence
Highly cited
179citations · ~26 / year
Intraoperative intercostal nerve cryoablation During the Nuss procedure reduces length of stay and opioid requirement: A randomized clinical trial.
Summary
The purpose of this study is to determine whether cryoanalgesia provides better pain control for minimally invasive pectus excavatum repair (the Nuss procedure) than thoracic epidural.
Linked Publications
-
Intraoperative intercostal nerve cryoablation During the Nuss procedure reduces length of stay and opioid requirement: A randomized clinical trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Length of Hospitalization |
3; 5 | — |
| SECONDARY Narcotic Usage |
268; 684 | — |
| SECONDARY Mean Neuropathic Pain Score at One Year |
2.4; 1.9 | — |
| SECONDARY Cost Analysis |
— | — |
Eligibility Criteria
Inclusion Criteria
- scheduled for Nuss procedure for pectus excavatum correction
- at least 13 years old at the time of the procedure
Exclusion Criteria
- age less than 13 years at time of procedure
- use of pain medication prior to procedure
- pectus carinatum, Poland's syndrome, or any chest wall anomaly other than pectus excavatum
- previous repair of pectus excavatum by any technique
- previous thoracic surgery
- congenital heart disease
- bleeding dyscrasia
- major anesthetic risk factors or history of previous problem with anesthesia
- pregnancy
- inability to communicate in English
Data sourced from ClinicalTrials.gov (NCT02721017) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.