Phase 3
Completed N=97
Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
Source: ClinicalTrials.gov NCT02725008 ↗Enrolled (actual)
97
Serious AEs
2.1%
Results posted
Feb 2019
Primary outcomePrimary: Treatment Failure — 6; 3 Participants — p=0.3
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the pediatric emergency department.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Treatment Failure |
6; 3 | 0.3 |
| SECONDARY Change in Symptom Severity From Day 1 to Day 5 |
-4; -4 | 0.95 |
Eligibility Criteria
Inclusion Criteria
- History of asthma defined as at least two (2) prior episodes of respiratory illness characterized by wheezing treated with inhaled beta agonists
Exclusion Criteria
- pregnancy
- severe chronic cardiac, respiratory, neurological or neuromuscular disease
- complete resolution of symptoms after one treatment of beta agonists
- severe asthma symptoms as defined by a Pulmonary Index Score of 12 or greater
Data sourced from ClinicalTrials.gov (NCT02725008). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.