N/A N=206 Randomized Single-blind Treatment

EmergeNcy Department Apneic Oxygenation Versus Usual Care During Rapid Sequence Intubation

Diffuse Apneic Oxygenation

Bottom Line

View on ClinicalTrials.gov: NCT02737917 ↗

Enrolled (actual)

206

Serious AEs

0.0%

Results posted

Mar 2019

Primary outcome: Primary: Mean (Average) Arterial Oxygen Saturation — 92; 93 Percent Saturation (SpO2)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Oxygen (Other); Standard of care (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: New York City Health and Hospitals Corporation
Primary completion: Dec 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Mean (Average) Arterial Oxygen Saturation	92; 93	—
SECONDARY Rates of Desaturation	17; 15; 3; 4; 80; 81	—

Summary

To determine the impact, if any the application of oxygen during the apnea period of rapid sequence intubation has on patients being intubated in the emergency department.

Eligibility Criteria

Inclusion Criteria

Any patient greater than 18 years of age that presents to the Lincoln medical and Mental Health Center Emergency Department requiring endotracheal intubation.

Exclusion Criteria

Patients will be excluded from the primary outcome analysis, but included in the intention to treat analysis for the secondary outcome if they are not pre-oxygenated to the standard RSI protocol of 3 minutes with 100% fraction of inspired oxygen (FiO2) by means of bag valve mask, HFNC and/or non-rebreather; patients will be excluded from the study in general if they are in cardiac or traumatic arrest or they are intubated without an apneic period (awake intubation)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02737917). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.