N/A
Completed N=24
Clinical Outcomes Maxilla: Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anesthesia
Source: ClinicalTrials.gov NCT02747186 ↗
Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Dec 2018
Primary outcomePrimary: Mean Time to Pulpal Response After Maxillary Molar Anesthesia — 98.8; 84.5 minutes
Summary
Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the buffered drug might be used with an effect equal to higher dosage not buffered. Clinical data are needed to confirm these anecdotal data. No published data exist comparing buffered local anesthetics at lower drug concentrations to current dosages commonly used in dental and oral surgical procedures
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Time to Pulpal Response After Maxillary Molar Anesthesia |
98.8; 84.5 | — |
| PRIMARY Mean Time to Pulpal Response After Maxillary Canine Anesthesia |
77.1; 70.9 | — |
Eligibility Criteria
Inclusion Criteria
- American Society of Anesthesiologists Risk Classification I Willingness to participate in two sessions
Exclusion Criteria
- Allergy to lidocaine class of anesthetic drugs Local anesthetic drug use in past week Current symptoms teeth or oral mucosa
Data sourced from ClinicalTrials.gov (NCT02747186). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.