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N/A N=45 Randomized Treatment

The Assessment of Patient Specific Instrumentation for Unicompartmental Knee Replacement

Knee Arthritis

Enrolled (actual)
45
Serious AEs
4.4%
Results posted
Nov 2021
Primary outcome: Primary: Radiological Assessment of Component Positioning — 0.9; 1.8; 9.1; 8.8 Degrees — p=<0.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Patient Specific Instrumentation (Procedure); Conventional Instrumentation (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Oxford University Hospitals NHS Trust
Primary completion
Feb 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Radiological Assessment of Component Positioning
0.9; 1.8; 9.1; 8.8; 3.5; 8.8 <0.05 sig
SECONDARY
Assessment of Functional Outcome
18.3; 18.2 <0.05 sig

Summary

Patient-specific instrumentation guides have previously been used to improving surgical accuracy and ease of implantation during Total Knee Replacement but have received less attention for implanting Unicompartmental Knee Replacement. The aim of this prospective study is to compare the accuracy of implantation and functional outcome of mobile bearing medial Unicompartmental Knee Replacement implanted with and without patient specific instrumentation by experienced knee surgeons.

Eligibility Criteria

Inclusion Criteria

  • Both cruciate ligaments functionally intact
  • Full thickness cartilage in the lateral compartment
  • Correctable intra-articular varus deformity
  • Full thickness cartilage loss in the medial compartment

Exclusion Criteria

  • Contra-indication for MRI
  • All forms of inflammatory arthritis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02748096). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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