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N/A N=65 Randomized Treatment

Physiological Augmentation of Mindfulness Meditation

Post Traumatic Stress Disorder

Enrolled (actual)
65
Serious AEs
0.0%
Results posted
Oct 2022
Primary outcome: Primary: Multiscale Dissociation Inventory (MDI) Score — 53.19; 61.58; 47.15; 51.00 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Breath-Focused Meditation (Other); Physiological Feedback (Device)
Age
Adult, Older Adult · 21+ yrs
Sex
Female
Sponsor
Emory University
Primary completion
Sep 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Multiscale Dissociation Inventory (MDI) Score
53.19; 61.58; 47.15; 51.00; 44.11; 47.94
PRIMARY
Modified PTSD Symptom Scale (MPSS) Score
27.33; 28.82; 19.63; 20.97; 17.58; 19.44
PRIMARY
Kentucky Mindfulness Scale Score
122.19; 117.55; 125.37; 125.79; 124.58; 126.65
PRIMARY
Multidimensional Assessment of Interoceptive Awareness Score
98.22; 86.45; 107.37; 106.92; 110.63; 105.29

Summary

The purpose of the study is to compare the efficacy of a physiologically-augmented breath-focused mindfulness-based intervention to reduce symptoms of dissociation that are associated with psychological trauma, as well as symptoms of posttraumatic stress disorder (PTSD). The study will evaluate whether physiological augmentation produces a greater change in dissociative symptoms, meditative engagement and attentional control, compared to non-augmented mindfulness. The augmentation comprises physiological feedback in the form of a vibration on the wrist. Vibrations are delivered by a device that will be placed on a participant's arm; the device vibrates in proportion to the person's breath.

Eligibility Criteria

Inclusion Criteria

  • Experience of at least one Criterion A trauma
  • Presence of current symptoms of post traumatic stress disorder (PTSD) that are significantly interfering with functioning
  • Multiscale Dissociation Inventory depersonalization score of 7
  • Fulfill at least two of the Clinician Administered PTSD Subscale criteria of clinically significant re-experiencing, avoidance, alterations in mood and cognitions, hyperarousal
  • Willingness to participate in the study

Exclusion Criteria

  • Actively psychotic
  • Cognitively compromised
  • Pregnancy
  • Substance or Alcohol Dependence
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02754557). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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