N/A N=36 Randomized Single-blind Prevention

The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery

Lung Neoplasms

Bottom Line

View on ClinicalTrials.gov: NCT02757092 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2020

Primary outcome: Primary: Discharge 2weeks Exercise Capacity — 408.61; 311.94 meter(M) — p=<0.05

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Home-based Pulmonary Rehabilitation (Other)
Age: Older Adult · 65+ yrs
Sex: All
Sponsor: Chang Gung Memorial Hospital
Primary completion: Apr 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Discharge 2weeks Exercise Capacity	408.61; 311.94	<0.05 sig
PRIMARY Discharge 6 Weeks Exercise Capacity	411.63; 332.94	<0.05 sig
PRIMARY Discharge 12 Weeks Exercise Capacity	397.06; 345.17	<0.05 sig
SECONDARY Discharge 2 Weeks Forced Vital Capacity (FVC in Liter(L)/Sec)	2.48; 2.00	<0.05 sig
SECONDARY Discharge 2weeks Forced Expiratory Volume in 1 Second(FEV1,Liter(L)/Sec)	1.97; 1.57	<0.05 sig
SECONDARY Discharge 2weeks MMEF 25-75%(Liter(L)/Sec)	2.00; 1.58	<0.05 sig
SECONDARY Discharge 2weeks Peak Expiratory Flow Rate(PEFR , Liter(L)/Sec)	5.68; 4.27	<0.05 sig
SECONDARY Discharge 2weeks Inspiratory Muscle Strength(MIP,cmH2O)	90.00; 67.33	<0.05 sig
SECONDARY Discharge 2weeks Expiratory Muscle Strength(MEP,cmH2O)	89.44; 68.89	<0.05 sig
SECONDARY Discharge 2 Weeks Modified Borg Score	1.06; 1.72	<0.05 sig
SECONDARY Discharge 2weeks Lung Expansion Capacity	1450.00; 1033.33	<0.05 sig
SECONDARY Postoperative 2 Weeks Pulmonary Complications	0; 1; 1; 2; 0; 1	0.05
SECONDARY Discharge 6 Weeks Forced Vital Capacity(Liter(L)/Sec)	2.48; 1.97	<0.05 sig
SECONDARY Discharge 6 Weeks Forced Expiratory Volume in 1 Second (FEV1,Liter(L)/Sec)	2.02; 1.58	<0.05 sig
SECONDARY Discharge 6weeks MMEF 25-75%(Liter(L)/Sec)	2.12; 2.08	<0.05 sig
SECONDARY Discharge 6weeks Peak Expiratory Flow Rate(PEFR in Liter( L)/Sec)	5.13; 4.71	<0.05 sig
SECONDARY Discharge 6 Weeks Inspiratory Muscle Strength(MIP,cmH2O)	93.33; 64.67	—
SECONDARY Discharge 6weeks Expiratory Muscle Strength (MEP, cmH2O)	93.89; 76.67	<0.05 sig
SECONDARY Discharge 6 Weeks Modified Borg Score	0.75; 1.11	<0.05 sig
SECONDARY Discharge 6weeks Lung Expansion Capacity	1683.33; 1116.63	<0.05 sig
SECONDARY Postoperative 6weeks Pulmonary Complications	0; 1; 0; 2; 3; 4	<0.05 sig
SECONDARY Discharge 12 Weeks Forced Vital Capacity (FVC in Liter(L)/Sec )	2.32; 2.16	<0.05 sig
SECONDARY Discharge 12 Weeks Forced Expiratory Volume in 1 Second(FEV1,Liter(L)/Sec)	1.85; 1.74	<0.05 sig
SECONDARY Discharge 12 Weeks MMEF 25-75%(Liter(L)/Sec)	2.44; 1.85	<0.05 sig
SECONDARY Discharge 12 Weeks Peak Expiratory Flow Rate (PEFR in Liter(L)/Sec)	4.94; 4.78	<0.05 sig
SECONDARY Discharge 12 Weeks Inspiratory Muscle Strength (MIP,cmH2O)	91.11; 64.67	—
SECONDARY Discharge 12weeks Expiratory Muscle Strength(MEP,cmH2O)	92.56; 74.48	<0.05 sig
SECONDARY Discharge 12 Weeks Modified Borg Score	0.70; 1.05	<0.05 sig
SECONDARY Discharge 12 Weeks Lung Expansion Capacity	1406.67; 1150.33	<0.05 sig
SECONDARY Postoperative 12 Weeks Pulmonary Complications	0; 1; 1; 2; 0; 1	—

Summary

The advantages of thoracoscopic surgery include smaller wounds, fewer postoperative complications, and shortened hospital stay. However,complications such as pain, pulmonary function insufficiency, pneumonia,postoperative pneumothorax, persistent air leakage, subcutaneous emphysema, cough, and hemoptysis may occur in older patients after thoracoscopic surgery. Pulmonary rehabilitation has been demonstrated by evidence-base medicine could effectively reduce pulmonary complications and dyspnea as well as improve lung function, quality of life, exercise ability, and functional status of patients after traditional heart and thoracic surgery. Studies have suggested that pulmonary rehabilitation should be performed for at least 4 weeks to optimize the training effect .However, most patients who undergo thoracoscopic surgery were discharged within 3-5 days. Such a short hospital stay impeded the delivery of pulmonary rehabilitation. Home-based pulmonary rehabilitation appeared to be an option for these patients The purpose of this study is to determine whether Pulmonary rehabilitation are effective on patients who had thoracic surgeries.

Eligibility Criteria

Inclusion Criteria

Signed consent
The men and women over the age of 65
admission to undergo VATS.
consciousness and ability to communicate
ability to undergo 6 weeks of a home-based pulmonary rehabilitation program

Exclusion Criteria

refusal to participate
unplanned emergency surgery
hemodynamic instability
received other surgery within a month postsurgery
unconsciousness after surgery
bedridden and upper or lower limb weakness
received radiation and chemotherapy postsurgery
implementation of thoracoscopic surgery for biopsy only

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Data sourced from ClinicalTrials.gov (NCT02757092). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.