N/A
N=49
Motor Imagery Intervention for Improving Gait and Cognition in the Elderly
Motor Activity
Bottom Line
View on ClinicalTrials.gov: NCT02762604 ↗Enrolled (actual)
49
Serious AEs
2.0%
Results posted
Jun 2024
Primary outcome: Primary: Change in Walking Speed During Single and Dual-task Walking Conditions — -3.33; -0.53; 5.89; -10.55 centimeters per second
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Imagined Gait Intervention (Behavioral); Visual Imagery Intervention (Behavioral)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Albert Einstein College of Medicine
- Primary completion
- Jun 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Walking Speed During Single and Dual-task Walking Conditions |
-3.33; -0.53; 5.89; -10.55 | — |
| SECONDARY Change in Cognitive Performance During Walking While Talking |
0.19; -1.54 | — |
| SECONDARY Change in Blood-oxygen-level-dependent (BOLD) Signal During Dual-task Imagined Walking While Talking (iWWT) Conditions |
-2.98; -3.07 | — |
| SECONDARY Change in Trail Making Test Form A |
-0.72; -1.45 | — |
| SECONDARY Change in Trail Making Test Form B |
4.49; -9.54 | — |
| SECONDARY Change in Trail Making Test Form B Minus Form A |
5.22; -8.09 | — |
| SECONDARY Change in Letter Number Sequencing Task Score |
-0.55; 0.61 | — |
| SECONDARY Change in Stroop Interference Test: Color-Word Minus Color Score |
-8.38; -14.47 | — |
| SECONDARY Change in Flanker Interference Task |
-49.55; -94.69 | — |
| SECONDARY Change in Stride Length |
3.08; -11.49 | — |
| SECONDARY Change in Gait Variability |
-0.17; 1.81 | — |
| SECONDARY Change in Gait Domains |
— | — |
Summary
The investigators propose a single-blind randomized clinical trial to determine if seniors show improved mobility (walking speed) and cognition following motor imagery (imagined walking) training. They hypothesize that imagined walking can be used as a rehabilitative tool for improving walking speed and cognition in the elderly, because it engages and strengthens similar neural systems as actual walking and cognition.
Eligibility Criteria
Inclusion Criteria
- Adults between 65 and 85 years and older, residing in the community.
- Able to speak English at a level sufficient to undergo study procedures.
- Plan to be in the area for the next 3 months.
Exclusion Criteria
- Presence of dementia (telephone-based memory impairment screen 1)
- Presence of gait disorder diagnosed by clinician (e.g. neuropathy).
- Any medical condition or chronic medication use (e.g. neuroleptics) that will compromise safety or affect cognitive functioning.
- Terminal illness with life expectancy <12 months.
- Progressive, degenerative neurologic disease (e.g. Parkinson's disease, ALS).
- Major psychiatric disorders such as Schizophrenia.
- Pacemaker or any permanent metal implants like hip prosthesis (other than tooth fillings) and claustrophobia.
Data sourced from ClinicalTrials.gov (NCT02762604). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.