N/A
N=112
Heart Rate Reducing Therapy in Cardiac CT Using Ivabradine and Bisoprolol
Bradycardia
Bottom Line
View on ClinicalTrials.gov: NCT02764970 ↗Enrolled (actual)
112
Serious AEs
0.0%
Results posted
Mar 2018
Primary outcome: Primary: Heart Rate — 65.1; 62.7 beats per minute
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Ivabradine 7.5mg orally (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Medical University of Graz
- Primary completion
- Sep 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Heart Rate |
65.1; 62.7 | — |
| SECONDARY Number of Participants With Use of i.v. Betablocker |
19; 17 | — |
| SECONDARY Radiation Dose |
12.9; 13.2 | — |
| SECONDARY Motion Artifacts |
5; 3.5 | — |
Summary
Out-patients scheduled for coronary computer tomographic angiography (CCTA) were screened regarding their baseline heart rate. If heart rate was > 75, patients were pretreated with 10mg bisoprolol (group 1) or 10mg bisoprolol plus 7.5mg ivabradine (group 2) to reduce heart rate one our before CCTA was performed.
Heart rate, additional use of i.v. bradycardic agents, motion artefacts, radiation dose and drug tolerance was monitored.
Eligibility Criteria
Inclusion Criteria
- all comer study
Exclusion Criteria
- none
Data sourced from ClinicalTrials.gov (NCT02764970). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.