N/A N=75 Randomized Supportive Care

Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial

Arthroplasty, Replacement, Knee

Bottom Line

View on ClinicalTrials.gov: NCT02773537 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2019

Primary outcome: Primary: Pain Measurement Via VAS (Visual Analog Scale) — 4.11; 4.68; 4.36 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Femoral nerve catheter and sciatic nerve block (Drug); Adductor canal catheter and selective tibial block (Drug); Adductor canal catheter only (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Medical University of South Carolina
Primary completion: Nov 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Pain Measurement Via VAS (Visual Analog Scale)	4.11; 4.68; 4.36	—
SECONDARY Narcotic Requirements	90; 107.5; 107	—
SECONDARY Functional Outcome Measures- Exstension/Knee Buckling	13; 15; 22; 20; 7; 8	—
SECONDARY Functional Outcome Measures- AMPAC (Activity Measure for Post-Acute Care)	15.0; 16.5; 16.0	—
SECONDARY Functional Outcome Measures- TUG (Timed Up and Go)- Distance Walked	80; 155; 160	—
SECONDARY Functional Outcome Measures- TUG (Timed Up and Go)- Time in Seconds	66.1; 61.9; 65.3	—
SECONDARY Patient Reported Pain and Function Outcomes	66.8; 72.6; 70.5; 64.3; 71.7; 67.4	—
SECONDARY Patient Reported Pain and Function Outcomes	66.8; 72.6; 70.5; 64.3; 71.7; 67.4	—

Summary

The primary aim of this pilot study will be to develop a clinically meaningful, patient-centric, and pragmatic protocol to evaluate the comparative effectiveness of different strategies for achievement of the ideal balance between analgesia and functional mobility following total knee arthroplasty (TKA).

Eligibility Criteria

Inclusion Criteria

Males and Females 18 years of age or older
Undergoing elective primary total knee arthroplasty
Patient is willing and able to give consent and participate

Exclusion Criteria

Inability to receive spinal anesthesia or peripheral nerve block
Non-ambulatory patients
Non- English speaking patients
Vulnerable populations including prisoners

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02773537). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.