N/A
Completed N=220
Comparison of Vibrating Mesh Nebulizer Versus Jet Nebulizer in the Pediatric Asthma Patient
Source: ClinicalTrials.gov NCT02774941 ↗Enrolled (actual)
220
Serious AEs
0.0%
Results posted
Jan 2020
Primary outcomePrimary: Number of Subjects Hospitalized — 22; 15 Participants
Summary
The purpose of this study is to compare clinical outcomes related to the current practice of using a jet nebulizer (JN) with aerosol mask (AM) or mouthpiece (MP) versus a vibrating mesh nebulizer (VMN) with a valved-mask (VM) or MP in the treatment of acute moderate to severe asthma in Children's Medical Center Dallas Emergency Department (CMCED).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Subjects Hospitalized |
22; 15 | — |
| SECONDARY Number of Treatments Required to Achieve Mild Asthma Score - Discharge Criteria |
3.0; 2 | — |
Eligibility Criteria
Inclusion Criteria
2 to 18 year old (up to 19th birthday) otherwise healthy children with primary diagnosis of acute moderate to severe exacerbation of asthma presenting to Children's Medical Center Emergency Department, Dallas
-
Exclusion Criteria
- Children < 2 years old
- Children with comorbid/complex medical conditions such as: congenital or acquired cardiovascular disease, cystic fibrosis, chronic lung disease (other than asthma), bronchopulmonary dysplasia, airway anomalies (e.g., tracheomalacia) or immunodeficiency syndromes.
- Patients with coexisting medical condition such as pneumonia
- Patients in impending respiratory failure as determined by treating physician
- Patients that have had oral corticosteroids within 24hrs of CMCED admission
- Patients that have had bronchodilator treatment within one hour of CMCED admission
Data sourced from ClinicalTrials.gov (NCT02774941). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.