Phase 2
Completed N=48
Adipose Tissue Extract and Platelet-rich Plasma Use for Wound Healing
Wound Healing Disturbance of
Source: ClinicalTrials.gov NCT02799290 ↗
Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcomePrimary: Wound Re-epithelization — 12.34; 10.27; 11.33 days
Summary
Adipose Tissue Extract (ATE) has been found to be an autologous source of growth factors with proven in vitro angiogenic and adipogenic properties.It is obtained by a simple lipoaspirate procedure. We sought to compare the effect of ATE with another known source, platelet-rich plasma to compare the wound healing characteristics on skin graft donor sites.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Wound Re-epithelization |
12.34; 10.27; 11.33 | — |
| SECONDARY Scar Properties |
8.13; 4.86; 6.46; 6.85; 5.66; 2.4 | — |
| SECONDARY Oxygenated Hemoglobin |
0.36; 0.20; 0.24; 0.28; 0.18; 0.19 | — |
| SECONDARY Melanin Concentration in Wound |
0.02; 0.03; 0.03; 0.03; 0.01; 0.02 | — |
Eligibility Criteria
Inclusion Criteria
- donor site indication
Exclusion Criteria
- immunosupressive states
- terminal renal insufficiency
- pregnancy
- coagulation dyscrasias
- active infection in donor site
Data sourced from ClinicalTrials.gov (NCT02799290). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.