N/A
N=21
Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Bottom Line
View on ClinicalTrials.gov: NCT02803164 ↗Enrolled (actual)
21
Serious AEs
61.9%
Results posted
Sep 2021
Primary outcome: Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Wound Vacuum-assisted dressing (Device); Control group (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Nov 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Duration of Negative Pressure Wound Therapy (NWPT) |
8 | — |
| SECONDARY Wound Closure |
7; 18 | — |
| SECONDARY Length of Hospital Stay |
6; 25 | — |
Summary
Vacuum-assisted dressings (V-AD) are effective in treating patients with open chest wounds (OCW) and will decrease the time-to-closure of such wounds when compared to a historical cohort of patients managed by traditional wound care management.
Eligibility Criteria
Inclusion Criteria
- Subject is scheduled to undergo surgical intervention(s) as part of the standard care for management of intra-thoracic infection.
Exclusion Criteria
- Patent bronchopleural fistulas. Severe respiratory failure requiring mechanical ventilation at the time of first consultation.
- Proven or suspected malignancy in the wound. Coagulopathy due to medical or pharmacologic reasons. Dependency on anticoagulants or antiplatelet medication due to high risk for adverse events if these medications are stopped for a prolonged period of time.
Allergy to acrylic products.
Data sourced from ClinicalTrials.gov (NCT02803164). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.