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N/A Completed N=58

Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation

Source: ClinicalTrials.gov NCT02818218 ↗
Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcomePrimary: Central Venous Pressure (CVP) — 11.7 mmHg

Summary

Consecutive patients undergoing liver transplant surgery will be included in the study. Before surgical incision, during the preanhepatic phase, during the anhepatic phase, during the postanhepatic phase and following closure of the deep fascial layer of the anterior abdominal wall simultaneous measurement of SVC diameter, SBC collapsibility index and CVP will be recorded.

Outcome Measures

OutcomeResultp-value
PRIMARY
Central Venous Pressure (CVP)
11.7
PRIMARY
Correlation of Central Venous Pressure (CVP) and Superior Vena Cava (SVC) Collapsibility Index
26 0.944
PRIMARY
Correlation of Central Venous Pressure (CVP) and Minimum Diameter of Superior Vena Cava (SVC)
12.8 <0.001 sig
PRIMARY
Correlation of Central Venous Pressure (CVP) and Maximum Diameter of Superior Vena Cava (SVC)
17.3 <0.001 sig
SECONDARY
Cardiac Index
4.4
SECONDARY
Correlation of Cardiac Index (CI) and Superior Vena Cava (SVC) Collapsibility Index
26 0.298
SECONDARY
Correlation of Cardiac Index (CI) and Minimum Diameter of Superior Vena Cava (SVC)
12.8 0.002 sig
SECONDARY
Correlation of Cardiac Index (CI) and Maximum Diameter of Superior Vena Cava (SVC)
17.3 <0.001 sig

Eligibility Criteria

Inclusion Criteria

  • 18 years of age
  • undergoing liver transplantation surgery (cadaveric and living related)

Exclusion Criteria

  • Contraindication to Transesophageal echocardiography
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02818218). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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