N/A
N=58
Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver Transplantation
Liver Failure
Bottom Line
View on ClinicalTrials.gov: NCT02818218 ↗Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Aug 2025
Primary outcome: Primary: Central Venous Pressure (CVP) — 11.7 mmHg
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Liver Transplant (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- The Cleveland Clinic
- Primary completion
- May 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Central Venous Pressure (CVP) |
11.7 | — |
| PRIMARY Correlation of Central Venous Pressure (CVP) and Superior Vena Cava (SVC) Collapsibility Index |
26 | 0.944 |
| PRIMARY Correlation of Central Venous Pressure (CVP) and Minimum Diameter of Superior Vena Cava (SVC) |
12.8 | <0.001 sig |
| PRIMARY Correlation of Central Venous Pressure (CVP) and Maximum Diameter of Superior Vena Cava (SVC) |
17.3 | <0.001 sig |
| SECONDARY Cardiac Index |
4.4 | — |
| SECONDARY Correlation of Cardiac Index (CI) and Superior Vena Cava (SVC) Collapsibility Index |
26 | 0.298 |
| SECONDARY Correlation of Cardiac Index (CI) and Minimum Diameter of Superior Vena Cava (SVC) |
12.8 | 0.002 sig |
| SECONDARY Correlation of Cardiac Index (CI) and Maximum Diameter of Superior Vena Cava (SVC) |
17.3 | <0.001 sig |
Summary
Consecutive patients undergoing liver transplant surgery will be included in the study. Before surgical incision, during the preanhepatic phase, during the anhepatic phase, during the postanhepatic phase and following closure of the deep fascial layer of the anterior abdominal wall simultaneous measurement of SVC diameter, SBC collapsibility index and CVP will be recorded.
Eligibility Criteria
Inclusion Criteria
- 18 years of age
- undergoing liver transplantation surgery (cadaveric and living related)
Exclusion Criteria
- Contraindication to Transesophageal echocardiography
Data sourced from ClinicalTrials.gov (NCT02818218). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.