N/A
N=19
Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV)
One-Lung Ventilation
Bottom Line
View on ClinicalTrials.gov: NCT02821455 ↗Enrolled (actual)
19
Serious AEs
0.0%
Results posted
Aug 2018
Primary outcome: Primary: Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation — 0.0807 Correlation coefficient
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Lung Surgery with One-Lung Ventilation (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Edinburgh
- Primary completion
- Nov 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation |
0.0807 | — |
| SECONDARY Correlation Between Bispectral Index (BIS) and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation. |
— | — |
Summary
The aims of the study is to determine if end-tidal concentrations of the anaesthetic gases isoflurane and sevoflurane as measured by a standard gas monitor are related to the blood levels during one-lung ventilation.
Eligibility Criteria
Inclusion Criteria
- Over the age of 18
- Admitted for elective thoracic surgery using one-lung ventilation obtained by the use of a double-lumen endotracheal tube or bronchial blocker.
- Elective surgery planned between 1 August and 30 November 2016
- Planned insertion of an arterial cannula by anaesthetist for routine monitoring of systemic arterial pressure
- Planned inhalational anaesthesia technique with isoflurane or sevoflurane.
- Patients who have provided consent to take part in the study
Exclusion Criteria
- Patients under the age of 18
- History of malignant hyperthermia
- Emergency thoracic surgery
- Patients who have not consented to take part in the study
Data sourced from ClinicalTrials.gov (NCT02821455). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.