N/A Completed N=19

Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV)

One-Lung Ventilation

Source: ClinicalTrials.gov NCT02821455 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2018

Primary outcomePrimary: Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation — 0.0807 Correlation coefficient

Summary

The aims of the study is to determine if end-tidal concentrations of the anaesthetic gases isoflurane and sevoflurane as measured by a standard gas monitor are related to the blood levels during one-lung ventilation.

Outcome Measures

Outcome	Result	p-value
PRIMARY Correlation Between Blood and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation	0.0807	—
SECONDARY Correlation Between Bispectral Index (BIS) and End-tidal Isoflurane or Sevoflurane Concentration During One-lung Ventilation.	—	—

Eligibility Criteria

Inclusion Criteria

Over the age of 18
Admitted for elective thoracic surgery using one-lung ventilation obtained by the use of a double-lumen endotracheal tube or bronchial blocker.
Elective surgery planned between 1 August and 30 November 2016
Planned insertion of an arterial cannula by anaesthetist for routine monitoring of systemic arterial pressure
Planned inhalational anaesthesia technique with isoflurane or sevoflurane.
Patients who have provided consent to take part in the study

Exclusion Criteria

Patients under the age of 18
History of malignant hyperthermia
Emergency thoracic surgery
Patients who have not consented to take part in the study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02821455). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.