N/A
Completed N=40
Clarithromycin as Adjuvant to Periodontal Debridement
Aggressive Periodontitis
Source: ClinicalTrials.gov NCT02829983 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Oct 2017
Primary outcomePrimary: Clinical Attachment Level — 2.71; 3.03 milimeter
Summary
To assess the periodontal clinical response and the possible adverse effects of the clarithromycin combined to periodontal mechanical therapy in the treatment of patients with generalized aggressive periodontitis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Clinical Attachment Level |
2.71; 3.03 | — |
| SECONDARY Probing Depth |
2.53; 2.86 | — |
Eligibility Criteria
Inclusion Criteria
- diagnosis of Generalized Aggressive Periodontitis
- presence of ≥20 teeth
- presence of ≥ 6 sites presenting probing depth (PD) ≥5mm with bleeding on probing (BOP) and ≥2 sites with PD ≥7mm (including incisors and first molars, in addition to two other non-contiguous teeth between them)
- good general health
- <35 years of age
- agree to participate in the study and sign a written consent
Exclusion Criteria
- pregnant or lactating
- suffering from any other systemic disease (e.g. cardiovascular, diabetes, blood dyscrasias, immunodeficiency, etc) which could alter the course of periodontal disease
- received antimicrobials in the previous 6 months
- taking long-term anti-inflammatory drugs
- received a course of periodontal treatment within the last 12 months
- smoked
Data sourced from ClinicalTrials.gov (NCT02829983). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.