N/A
Completed N=90
The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
Perforated Appendicitis
Source: ClinicalTrials.gov NCT02881996 ↗
Enrolled (actual)
90
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcomePrimary: Time Until PCA Discontinued After the Operation — 76.4; 86.7 hours
Summary
The objective of this study is to evaluate two standard post-operative pain regimens routinely used after laparoscopic appendectomy for perforated appendicitis. The investigators hypothesize that the use of intravenous (IV) acetaminophen in addition to IV ketorolac with narcotic pain pump will decrease time to transition off patient/nurse controlled analgesia (PCA) to oral pain medications.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Time Until PCA Discontinued After the Operation |
76.4; 86.7 | — |
| SECONDARY Postoperative Duration of Hospital Stay |
3.9; 4.5 | — |
Eligibility Criteria
Inclusion Criteria
- All patients ages 2-17 years old undergoing laparoscopic appendectomy at CMH found to have perforated appendicitis.
Exclusion Criteria
- Non-perforated appendicitis
- Normal appendix at the time of operation or other associated conditions causing abdominal pain
- Patients with history of chronic pain
- Known underlying liver disorders
- Known allergy to pain medication in protocol
- Non-English speaking
Data sourced from ClinicalTrials.gov (NCT02881996). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.