N/A
N=130
Comparison Between End-to-side and Side-to-side Anastomosis After Laparoscopic Right Hemicolectomy
Anastomosis
Bottom Line
View on ClinicalTrials.gov: NCT02897531 ↗Enrolled (actual)
130
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Cumulative Recovery Rate — 100; 100 percentage of participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- ES anastomosis (Procedure); SS anastomosis (Procedure)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Seoul National University Hospital
- Primary completion
- Aug 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Cumulative Recovery Rate |
100; 100 | — |
| SECONDARY Postoperative Hospital Stay |
5; 6 | — |
| SECONDARY Postoperative Complications |
11; 8 | — |
| SECONDARY Failure Rate of the Enhanced Recovery Program |
7; 5 | — |
| SECONDARY Readmission Rate Within 1 Month After Surgery |
3; 2 | — |
Summary
The purpose of this study is to evaluate the efficacy of end-to-side anastomosis after laparoscopic right hemicolectomy compared with that of side-to-side anastomosis. The investigators hypothesize that the end-to-side anastomosis may be associated with superior recovery compared with side-to-side anastomosis after laparoscopic right hemicolectomy under enhanced recovery program. The primary endpoint is the cumulative recovery rate, consisting of the recovery time of diet, pain, ambulation, and afebrile status.
Eligibility Criteria
Inclusion Criteria: Patients who have all of the following:
- Age: 18 - 80
- Right-sided colon cancer (adenocarcinoma, located in cecum to hepatic flexure)
- Appropriate laboratory (Bone marrow) findings (Hemoglobin ≥ 10g/dl, White blood cell count ≥ 4,000/mm3, Platelet ≥ 100,000/mm3)
- Appropriate renal function (Creatinine ≤ 1.5 mg/dl)
- Appropriate cardio-pulmonary functions
- Appropriate understanding of the study and provide the informed consent
Exclusion Criteria: Patients who have 1 or more of the following:
- Distant metastasis or locally advanced tumor which required combined resection of other organs, such as the ureter, duodenum, or small bowel.
- Not suitable for laparoscopic surgery
- Currently taking medication for dyschezia, such as constipation or diarrhea.
- Not suitable for adapting enhanced recovery program due to underlying diseases, such as cardio-pulmonary disease, mental disorder, and etc.
- Not suitable for participation in this clinical trial based on the judgment of the investigators
Data sourced from ClinicalTrials.gov (NCT02897531). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.