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N/A N=39 Randomized Triple-blind Basic Science

Shifting Salty Taste Preferences in Children

Development

Enrolled (actual)
39
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcome: Primary: Most Preferred Level of Salt Taste — 0.44; 0.34; 0.42; 0.43 mol/L — p=0.30

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Low Sodium Group (Other)
Age
Pediatric, Adult, Older Adult · 7+ yrs
Sex
All
Sponsor
Monell Chemical Senses Center
Primary completion
Aug 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Most Preferred Level of Salt Taste
0.44; 0.34; 0.42; 0.43 0.30
PRIMARY
Relative Preference for Regular vs Low Sodium Cereal
3; 5; 7; 4 <0.05 sig
SECONDARY
Salt Taste Detection Thresholds
4.4; 3.6; 4.6; 5.4 0.32
SECONDARY
Most Preferred Level of Sucrose
0.72; 0.57; 0.76; 0.64 0.77
SECONDARY
Intake of Cereal During Intervention Period
27.8; 19.3; 33.3; 17.9; 30.6; 18.9 <0.05 sig
SECONDARY
Blood Pressure
113.7; 115.5; 65.1; 66.6 >0.40

Summary

The goals of the proposed research are to determine whether repeated exposure to a low sodium food will result in reduced preference for salt in that food among children; and to determine whether such reductions in preference are related to dietary intake of salt, taste receptor genotype, and anthropometric and physiological measures.

Eligibility Criteria

Inclusion Criteria

  • Healthy
  • Willingness to consume no other cereals during intervention

Exclusion Criteria

  • Allergies and/or taking medication that affects taste
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02909764). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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