N/A Completed N=102 Randomized Single-blind Treatment

Evaluation of Web-Based CBT for Women Veterans With PTSD

Post-Traumatic Stress Disorder

Source: ClinicalTrials.gov NCT02917447 ↗

Enrolled (actual)

102

Serious AEs

11.8%

Results posted

May 2020

Primary outcomePrimary: Change in PTSD Checklist (PCL-5) — -13.1; -8.9; -13.8; -7.5 units on a scale — p=0.15

Summary

The purpose of this study is to evaluate an online PTSD intervention that was adapted for women Veterans, called DElivery of Self TRaining and Education for Stressful Situations-Women Veterans version (DESTRESS-WV). The intervention consists of structured online sessions as well as weekly brief phone calls for additional support with a study coach. Women Veterans with PTSD who are eligible will be randomized to receive either DESTRESS-WV or phone monitoring only for 8 weeks. Participants will be assessed immediately post-treatment as well as at 12 and 24 weeks post-treatment. Investigators hypothesize that participants randomly assigned to DESTRESS-WV will have a greater decrease in severity of PTSD symptoms compared to those randomly assigned to phone monitoring only.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in PTSD Checklist (PCL-5)	-13.1; -8.9; -13.8; -7.5; -11.4; -8.9	0.15
SECONDARY Change in Patient Health Questionnaire-8 (PHQ-8)	-3.8; -2.6; -3.5; -0.6; -2.3; -1.2	.049 sig
SECONDARY Change in the Quality of Life Enjoyment and Satisfaction Questionnaire - Short Form	9.1; 7.9; 4.3; 4.8; 3.0; 3.8	0.92

Eligibility Criteria

Inclusion Criteria

age 18 or older
female
Veteran of the US military
current PTSD
reports routine access to computer and Internet
willing to provide at least one collateral contact
willing to allow investigators to leave phone messages pertaining to the study
willing to be audio-taped during assessments and study coach calls

Exclusion Criteria

actively engaged in individual therapy in the past two months, or receiving couple's or group therapy in the past two months that focuses on PTSD
scheduled to receive a future individual therapy appointment or future couples' or group therapy appointment focused on PTSD at a frequency of once per month or more
active suicidal or violent ideation within the past two months or on the VA "high risk" list for imminent danger to self or others
moderate or extreme substance use disorder in the past year
acute psychosis, psychotic episode, or psychotic disorder diagnosis within the past year
unstable administration schedule or dosing of any antidepressant, anxiolytic, or sedative-hypnotic

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02917447). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.