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N/A Completed N=7 Randomized Prevention

E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia

Tobacco Smoking
Source: ClinicalTrials.gov NCT02918630 ↗
Enrolled (actual)
7
Serious AEs
0.0%
Results posted
Jul 2018
Primary outcomePrimary: Change in Smoking as Assessed by Breath Carbon Monoxide Levels — -18; -4.3 parts per million (ppm)

Summary

The purpose of this study is to assess if access to an electronic nicotine delivery device, or e-cigarette, in addition to nicotine patch (21 mg) can help reduce cigarette smoking among individuals diagnosed with schizophrenia compared to nicotine patch alone.

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Smoking as Assessed by Breath Carbon Monoxide Levels
-18; -4.3
PRIMARY
Change in Smoking as Assessed by Urinary Cotinine Levels
0; 0
PRIMARY
Number of Cigarettes Smoked Per Day as Assessed by Self-report Via Timeline Follow-back
9; 12
SECONDARY
Feasibility as Assessed by Percent of Participants Who Completed the Study
100; 100

Eligibility Criteria

Inclusion Criteria

  • Be diagnosed with schizophrenia
  • Be in stable medical condition (DSM-V)
  • report smoking ≥10 tobacco cigarettes/day
  • present a breath CO ≥10 ppm
  • report wanting to reduce their cigarette smoking
  • be fluent in English
  • have a stable living situation

Exclusion Criteria

  • be currently pregnant or breastfeeding
  • report wanting to quit smoking in the immediate future
  • test positive for illicit drugs except THC
  • have any illness, medical condition, or use of medications, which in the opinion of the study physicians would preclude safe and/or successful completion of the study
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02918630). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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