N/A
Completed N=12
Effect of Palm Olein Intake on Lipid Profile and Appetite Regulation
Lipidaemia
Source: ClinicalTrials.gov NCT02924896 ↗
Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcomePrimary: Change From Baseline in Appetite Hormones PYY — 58.5; 60; 56 mmol/L*min
Summary
Aims: To investigate whether acute ingestions of palm oil will have an effect on appetite regulation
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Appetite Hormones PYY |
58.5; 60; 56 | — |
| SECONDARY Change From Baseline in Glucose, |
1400; 1545; 1486 | — |
| SECONDARY Change From Baseline in Appetite Hormones GLP_1 |
43.8; 32; 55 | — |
Eligibility Criteria
Inclusion Criteria
- Healthy and overweight male and female volunteers of all ethnicities (body mass index (BMI) of 18.5-29.9 kg/m2)
- Age between 18-60 years (inclusive)
Exclusion Criteria
- Abnormal liver function test (elevated alanine aminotransferase and aspartate transaminase)/ abnormal kidney function test (elevated plasma creatinine)
- History of type 2 diabetes mellitus, cancer, stomach ulcers, drug abuse or alcoholism, gastrointestinal disorders like Crohn's disease
- Smokers
- On lipid/blood pressure- lowering medication/supplements
- Blood pressure>140/90 mm Hg
- Fasting total cholesterol > 6.2 mmol/L
- Fasting triacylglyceride > 2.0 mmol/L
- Subject must not be allergic to intervention
- Pregnancy and breastfeeding (pregnancy test will be undertaken at the screening visit)
- Subjects taking nutritional supplements or on any weight-loss programs
- Subjects who gained or lost ≥ 3kg weight in the past three months
- Subjects with history of hypo- and hyperthyroidism
- Subjects who are anaemic and those who donated blood within three months of the study
Data sourced from ClinicalTrials.gov (NCT02924896). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.