N/A
Completed N=864,080
CT DOSE Collaboratory
Ionizing Radiation Exposure · Quality Improvement
Source: ClinicalTrials.gov NCT03000751 ↗
Enrolled (actual)
864,080
Serious AEs
—
Results posted
Mar 2024
Primary outcomePrimary: Change in Mean Effective Dose (ED) — -0.13; -0.81; -0.14; -0.26 Millisieverts (mSv)
Summary
This is a pragmatic stepped-wedge cluster randomized controlled trial to explore variation in doses used for diagnostic CT by pooling radiation dose data across diverse healthcare delivery systems.
To compare different strategies for lowering and optimizing dose and identify the barriers and facilitators to implementing successful dose optimization strategies and standardizing practice.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Mean Effective Dose (ED) |
-0.13; -0.81; -0.14; -0.26; -0.88; -2.04 | — |
| PRIMARY Percentage of CT Scans With an Effective Dose Above Benchmark |
24.7; 24.7; 22.2; 26; 25.5; 24.9 | — |
| SECONDARY Mean Dose Length Product |
— | — |
| SECONDARY Proportion of CT Scans With a Dose Length Product Above Benchmark |
— | — |
| SECONDARY Change in Mean Volume Computed Tomography Dose Index (CTDIvol) |
0.09; 0.03; 0.04; -0.11; -0.05; -0.42 | — |
| SECONDARY Percentage of CT Scans With a CTDIvol Above Benchmark |
24.5; 24.9; 24.1; 26; 25.8; 24.1 | — |
| SECONDARY Change in Mean Organ Doses: Brain Dose for Head CT; Lung Dose For Chest CT; Colon and Liver Dose for Abdomen CT |
-6.0; -12.2; -2.1; -3.7; -16.0; -30.1 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnostic CT scans of the head, chest, and/or abdomen/pelvis performed within the study period
Exclusion Criteria
- non-diagnostic scans that are not of the head, chest, and/or abdomen/pelvis
Data sourced from ClinicalTrials.gov (NCT03000751). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.