N/A
Completed N=61
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Using a 22 vs 25-Gauge Needle
Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma · Lung Cancer
Source: ClinicalTrials.gov NCT03004586 ↗
Enrolled (actual)
61
Serious AEs
0.0%
Results posted
Jun 2022
Primary outcomePrimary: Percentage of Lymph Nodes With Adequate Samples — 79; 78.5 Percentage of Lymph Nodes
Summary
The goal of this clinical research study is to compare the effectiveness of a smaller, 25-gauge needle when used in an endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) instead of a standard 22-gauge needle.
The safety of the needles will also be studied.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Lymph Nodes With Adequate Samples |
79; 78.5 | — |
| SECONDARY Concordance With the Final Diagnosis |
82; 80.5 | — |
| SECONDARY Usability of the Needle |
4.27; 4.95; 4.58; 4.00; 4.40; 4.65 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18 years or older
- Indication for EBUS-guided needle biopsy based on suspicion of either benign or malignant disease in mediastinal or hilar lymph nodes.
Exclusion Criteria
- Patients who are pregnant or lactating
- Inability to give informed consent
- Patients in which only one lymph node station is expected to be sampled by the performing clinician.
Data sourced from ClinicalTrials.gov (NCT03004586). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.