Early Phase 1
Completed N=40
Exercise Training Effects on Metabolic Syndrome: Interactions With Medication
Exercise Therapy · Metabolic Syndrome X · Cardiorespiratory Fitness
Source: ClinicalTrials.gov NCT03019796 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
May 2021
Primary outcomePrimary: Systolic Blood Pressure — 126; 134; 124; 133 mmHg — p=0.040
Summary
To analyze the effects of different exercise training modalities (continuous, intervallic, and resistance training) on cardiorespiratory and metabolic fitness of metabolic syndrome patients when this training interacts with their habitual medication.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Systolic Blood Pressure |
126; 134; 124; 133 | 0.040 sig |
| PRIMARY Diastolic Blood Pressure |
75; 79; 72; 77 | 0.054 |
| PRIMARY Mean Arterial Pressure |
92; 97; 89; 96 | 0.040 sig |
| SECONDARY Maximal Oxygen Consumption Rate During Exercise (VO2max). |
2.26; 2.26; 2.49; 2.49 | 0.321 |
| SECONDARY Maximal Rate of Fat Oxidation. |
0.24; 0.24; 0.28; 0.28 | 0.401 |
| SECONDARY Body Weight |
92.1; 92.5; 90.0; 90.8 | 0.021 sig |
Eligibility Criteria
Inclusion Criteria
- Metabolic syndrome patients diagnosed according to the International diabetes federation consensus of 2009 (Alberti, et al., Circulation).
- 18-65 years old
Exclusion Criteria
Cardiovascular disease or musculo-skeletal that prevents them from being able to perform intense exercise.
- Respiratory failure
- Patient ends
- Pregnancy
Data sourced from ClinicalTrials.gov (NCT03019796). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.