N/A
Completed N=677
Unexpected Cardiac Arrest in Intensive Care Unit
Heart Arrest
Source: ClinicalTrials.gov NCT03021564 ↗
Enrolled (actual)
677
Serious AEs
1.0%
Results posted
Aug 2020
Primary outcomePrimary: Number of Patients With Unexpected Cardiac Arrest — 677; 30,722 Participants
Summary
Unexpected cardiac arrest involves approximately 0.5 to 5% of patients admitted in Intensive Care Unit (ICU). Even if they have a technical environment conducive to prompt diagnosis and prompt treatment, patients hospitalized in ICU suffer from chronic illnesses and organ failure(s) that obscure the prognosis of cardiac arrest. Although extra cardiac arrhythmias or intra-hospital arrests are the subject of numerous publications, few studies specifically focus on unexpected cardiac arrest in ICU (none in France). The objective of our work is to produce a prospective epidemiological description of unexpected cardiac arrest in in French ICUs.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Patients With Unexpected Cardiac Arrest |
677; 30,722 | — |
| SECONDARY Number of Patients Per Reason for ICU Admission |
100; 487; 37; 210; 22; 149 | — |
| SECONDARY History, Comorbidities Before Unexpected Cardiac Arrest |
75; 322; 37; 182; 47; 156 | — |
| SECONDARY Mc Cabe Score Before Unexpected Cardiac Arrest |
63; 269; 57; 288 | — |
| SECONDARY Knaus Score Before Unexpected Cardiac Arrest |
92; 392; 28; 165 | — |
| SECONDARY Organ Failure Score Before Unexpected Cardiac Arrest |
42; 195; 48; 177; 68; 269 | — |
| SECONDARY Number of Participants With Unexpected Cardiac Arrest Etiologies |
91; 445; 15; 164; 30; 92 | — |
| SECONDARY Number of Patients With Resumption of Spontaneous Cardiac Activity After Cardiopulmonary Resuscitation |
97; 381; 73; 223 | — |
| SECONDARY Cerebral Performance Category Scale at Hospital Discharge |
43; 92; 1; 8; 0; 2 | — |
| SECONDARY Cerebral Performance Category Scale at 6 Months |
36; 82; 0; 6; 0; 1 | — |
| SECONDARY Number of Patients With Unexpected Cardiac Arrest, Resuscitated Despite Previous Decision Not to Resuscitate |
2; 11 | — |
Eligibility Criteria
Inclusion Criteria
- Patient with unexpected cardiac arrest during his / her hospitalization in the ICU
- Patients who have benefited from at least one basic cardiopulmonary resuscitation technique by the ICU team to treat this circulatory arrest (external electric shock, external cardiac massage, adrenaline injection ...)
- Patients with multiple unexpected cardiac arrest during hospitalization will be included only for the first circulatory arrest.
Exclusion Criteria
- Patients with unexpected cardiac that have not been resuscitated.
- Patients in cardiac arrest at admission to ICU
Data sourced from ClinicalTrials.gov (NCT03021564). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.