N/A
N=51
Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical Patients
Post-operative Pulmonary Complications
Bottom Line
View on ClinicalTrials.gov: NCT03024112 ↗Enrolled (actual)
51
Serious AEs
0.0%
Results posted
Dec 2017
Primary outcome: Primary: Number of Participants With Post-operative Pulmonary Complications — 1; 2 Participants — p=0.680
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Heated humified high-flow nasal cannula Oxygen (Device); Standard oxygen therapy (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Colorado, Denver
- Primary completion
- Jun 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Post-operative Pulmonary Complications |
1; 2 | 0.680 |
| SECONDARY Hospital Length of Stay |
6.6; 9.5 | — |
| SECONDARY Lowest Oxygen Saturation Level Measured |
88; 84 | — |
| SECONDARY ICU Length of Stay |
2; 3.2 | — |
Summary
The Investigators goal was to study the effect of high flow nasal cannula oxygen (HFNC) on the rate of post-operative pulmonary complications in thoracic surgical patients. The Investigators hypothesis is that prophylactic HFNC oxygen, as compared to standard oxygen treatment, will reduce the incidence of postoperative pulmonary complications, improve post-operative pulmonary function, and reduce Intensive Care Unit (ICU) and hospital length of stay.
Eligibility Criteria
Inclusion Criteria
- Undergoing Thoracic surgery
- Planned admission to ICU after surgery
Exclusion Criteria
- Younger than 18
- Pregnant
- Breast feeding
- Known diagnosis of obstructive sleep apnea
- Current or previous lung transplant
- Pneumonectomy
- Home oxygen greater than 4L/minute
- Inability to adhere to assigned treatment prior to 48 hours of surgery or until transferred to a floor
Data sourced from ClinicalTrials.gov (NCT03024112). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.