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N/A N=47 Screening

Evaluation of the Performance of the Motus Cleansing System (MCS)

CRC

Enrolled (actual)
47
Serious AEs
0.0%
Results posted
Feb 2019
Primary outcome: Primary: Performance of MCS in Cleansing a Poorly Prepared Colon. — 46; 9 Participants — p=<0.01

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Motus Cleansing System (MCS) (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Motus GI Medical Technologies Ltd
Primary completion
May 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Performance of MCS in Cleansing a Poorly Prepared Colon.
46; 9 <0.01 sig

Summary

The study is multi-center study ,planned as a single arm, open trial, aimed at evaluating the performance and safety of a colon cleansing device during a colonoscopy procedure in a poorly prepared colons.

Eligibility Criteria

Inclusion Criteria

  • Subjects being considered for diagnostic, screening or surveillance colonoscopy
  • Subjects in the age range of 18-75 years inclusive
  • Subjects with BodyMass Index (BMI) within the range of 18.5-35 inclusive
  • Subject has signed the informed consent

Exclusion Criteria

  • Subjects with known Inflammatory Bowel Disease
  • Subjects with known diverticulitis disease or with prior incomplete colonoscopy due to diverticular disease
  • Subjects with known or detected (during colonoscopy) bowel obstruction
  • History of prior surgery to colon and/or rectum
  • ASA≥IV
  • Renal insufficiency (Creatinine ≥ 1.5mg /dL) (based on medical history)
  • Abnormal Liver enzymes (ALT/AST ≥ 2 times upper limits of normal) (based on medical history)
  • Subjects taking anticoagulants drugs (excluding aspirin) or dual antiplatelet therapy
  • Subjects with known coagulation disorder (INR >1.5).
  • Subjects treated with H2 receptor antagonists or proton pump inhibitors within the 72 hours prior to consuming the Bisacodyl
  • Subjects with active, ongoing lower GI bleeding with hemodynamic instability.
  • Subjects with known Mega Colon
  • Pregnancy (as stated by patient) or breast feeding
  • Subjects with altered mental status/inability to provide informed consent
  • Patients who have participated in another interventional clinical study in the last 2 months
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03026075). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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