N/A Completed N=84 Randomized Triple-blind Basic Science

Effects of MDMA on Emotional and Social Memories

Healthy

Source: ClinicalTrials.gov NCT03050541 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2018

Primary outcomePrimary: Probability of Accurately Recalling Visual Stimuli — .52; .50; .54 probability

Summary

The purpose of this study is to examine the effects of MDMA on encoding and retrieval of emotional and social memories in healthy young adults. The study will explore the effects on memory retrieval when the drug is administered 1) before encoding, and 2) before retrieval.

Outcome Measures

Outcome	Result	p-value
PRIMARY Probability of Accurately Recalling Visual Stimuli	.52; .50; .54	—
SECONDARY Probability of Accurately Recognizing Visual Stimuli	.82; .81; .84	—

Eligibility Criteria

Inclusion Criteria

Normal healthy males and females, aged 18-40 years.

Exclusion Criteria

any current medical condition requiring medication or abnormal electrocardiogram
current or past medical condition considered to be a contraindication for the study conditions
any current Axis I psychiatric disorder (APA, 1994) including Substance Use Disorder, or Anxiety Disorder or Major Depression in the past year, any history of psychosis
less than high school education
lack of fluency in English
night shift work
pregnancy, lactation, or plans to become pregnant
use of hormonal contraception

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03050541). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.