Phase 4
Completed N=50
Comparison of Two Techniques of IV Lidocaine on Propofol Injection Pain
Injections, Intravenous
Source: ClinicalTrials.gov NCT03057704 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcomePrimary: Patient Expression of Pain — 0.76; 0.04 units on a scale
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Intravenous lidocaine is commonly given through an intravenous (IV) line prior to injection of propofol to reduce the amount of pain during propofol injection. The investigators want to study if giving the lidocaine through the IV while the forearm on the same limb has a tourniquet applied to it to prevent "washing out" of the lidocaine prior to propofol injection helps reduce propofol injection pain.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Expression of Pain |
0.76; 0.04 | — |
| SECONDARY Subject's Recall of Injection Discomfort |
0.52; 0.04 | — |
| SECONDARY Investigators Rating of Patient Discomfort |
1.12; 0 | — |
Eligibility Criteria
Inclusion Criteria
- Any subject at North Carolina Baptist Hospital scheduled for a procedure in which they will receive propofol for sedation or anesthesia and will not be receiving any other medications prior to the propofol injection.
- Cases must be schedule to have a duration less than 60 minutes.
Exclusion Criteria
- Subjects are excluded if they cannot verbalize a rating of pain
- Subjects are excluded if they require intravenous medications prior to the study period
Data sourced from ClinicalTrials.gov (NCT03057704). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.