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N/A Completed N=530 Randomized Supportive Care

Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination

Asthma Childhood
Source: ClinicalTrials.gov NCT03066596 ↗
Enrolled (actual)
530
Serious AEs
0.0%
Results posted
Oct 2025
Primary outcomePrimary: Percentage of Participants With 1 or More Guideline-based Corrective Actions Taken — 241; 197 Participants — p=<.001

Summary

The overall goal of this research study is to test the effectiveness of a multifaceted and multi-level prompting intervention in a real world urban primary care office setting on improving provider-delivered guideline-based asthma care and reducing asthma morbidity among urban children with persistent or uncontrolled asthma.

Outcome Measures

OutcomeResultp-value
PRIMARY
Percentage of Participants With 1 or More Guideline-based Corrective Actions Taken
241; 197 <.001 sig
SECONDARY
Symptom Free Days (SFDs)
5.79; 6.41; 9.33; 9.17; 9.68; 10.33 0.174

Eligibility Criteria

Inclusion Criteria

The criteria listed below will apply to ~5,000 children from eMPI and eUC practices:

  • Physician-diagnosed asthma (based on EHR)
  • Persistent or uncontrolled asthma as per clinic assessment. Based on NHLBI guidelines, any one of the following: in past month, > 2 days/week with asthma symptoms, >2 days/week with rescue medication use, >2 days/month with nighttime symptoms, or > 2 episodes in the past year that required systemic corticosteroids
  • Age 2 and 12 years, inclusive

Additional inclusion criteria will apply to a subset of 512 of children whose caregivers will be interviewed to obtain caregiver-reported morbidity outcomes:

  • Caregiver is able to speak and understand either English or Spanish. Participants unable to read will be eligible as all surveys will be administered verbally by research personnel
  • Consent from the primary caregiver, caregiver permission for the child to participate as well as assent from the child (>7 years). If there are eligible siblings, only one child will be randomly selected

Exclusion Criteria

  • The child has other significant medical conditions, such as congenital heart disease, cystic fibrosis, or other chronic lung disease, that could interfere with the assessment of asthma-related measures

Additional exclusion criteria will apply to a subset of 512 children/caregivers as described above:

  • No access to a telephone to conduct follow-up surveys
  • Children in foster care or other situations in which consent cannot be obtained from a guardian
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03066596). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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