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N/A N=54 Randomized Single-blind Device Feasibility

Evaluation of X-ray, Acetabular Guides and CT in THR

Total Hip Replacement

Enrolled (actual)
54
Serious AEs
1.8%
Results posted
Feb 2026
Primary outcome: Primary: Acetabular Cup Anteversion Angle — 5.8; 3.7 degree

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Corin OPS™ (Device); 2D X-ray templating technology (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University Hospitals Coventry and Warwickshire NHS Trust
Primary completion
Jun 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Acetabular Cup Anteversion Angle
5.8; 3.7

Summary

Total hip replacement is one of the most successful surgical procedures of modern times, with over 80,000 performed each year in the UK. However, up to 5% of all primary hip replacements need to be revised within the first 10 years, and in many cases malposition of the acetabular (hip socket) component is implicated in the early failure. The standard method of positioning the acetabular component is for the surgeon to be guided by a combination of the visible anatomical landmarks within the surgical field, and the wider environment of the operating theatre. The advent of 3D printing has led to the development of custom-made surgical guides which can be used during surgery, in order to assist the surgeon in the positioning of instruments and devices. These surgical guides are manufactured based on CT or MRI imaging, and are designed to clearly indicate to the surgeon the desired location and orientation of bony cuts and implant positions. This study will test the hypothesis that an acetabular alignment guide combined with three-dimensional CT-based planning using the Corin OPS™ (Optimised Positioning System), provides more accurate component alignment following primary total hip replacement compared with the current standard treatment, with the aim of improving patient outcomes and reducing the risk of complications of total hip replacement.

Eligibility Criteria

Inclusion Criteria

  • All patients undergoing an elective primary unilateral total hip replacement (THR) under the care of an orthopaedic consultant at University Hospitals Coventry and Warwickshire NHS Trust
  • Provision of written informed consent.
  • Male or Female aged 18-70 years.
  • Able and willing to comply with all study requirements.

Exclusion Criteria

  • Those patients deemed by the treating clinician as unsuitable for an uncemented primary acetabular implant for reasons such as
  • Low demand patient
  • Osteoporosis
  • Significant acetabular bone loss
  • Patients with significant orthopaedic deformities (eg fused knee, hip or ankle).
  • Unable to undergo planning imaging (unable to stand or sit for X-rays, or to lie in a CT scanner).
  • Patients currently receiving ionising radiation treatment or scans for other medical conditions.
  • Previous entry in this trial (contralateral THR).
  • Participation in a clinical trial of an investigational medicinal product in the last 90 days.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03072706). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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