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N/A N=1,499 Randomized Double-blind Supportive Care

The Pharmacist Follows You and Your Medication From Hospital to Your Daily Life and Investigate What This Means to You

Cross-Sectional Study

Enrolled (actual)
1,499
Serious AEs
Results posted
Dec 2019
Primary outcome: Primary: Readmissions — 111; 98; 68 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
basic intervention (Other); extended intervention (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Lene V. Ravn-Nielsen
Primary completion
Apr 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Readmissions
111; 98; 68
PRIMARY
Admissions
243; 233; 189
PRIMARY
Emergency Department Visits
21; 19; 15
PRIMARY
Composite Endpoint, Admissions or Emergency Department Visits
243; 233; 193
SECONDARY
Drug-related Admissions
96; 95; 75
SECONDARY
Drug-related Readmissions
38; 34; 24
SECONDARY
Percentage of Medication Changes Accepted by GPs
66
SECONDARY
Medication Review Changes Accepted by Physicians (in Hospital)
61; 61
SECONDARY
Mortality
50; 42; 54
SECONDARY
Drug Related Mortality
6; 3; 5

Summary

Background It is well known that the transfer of a patient from hospital to the general practitioner is related with mistakes in the medication of the patient. A report from 2006 measure the number of drug related admissions in Denmark to be 69.000 to 162.000 per year. To reduce these mistakes, more and better communication between the health professionals are suggested. Furthermore medication reviews made by pharmacist seems to reduce the number of drug related readmissions and other drug related issues, which can lead to an economic cost reduction. Objective The aim of this study is to investigate the impact of medication review and better communication between the health professionals after discharge of a patient from hospital to the general practitioner. The effect is measured as reducing the number of readmissions and number of visits at the emergency department 30 days and six month after inclusion of the patient. Method This study was estimated to include 1500 participants. The patients were randomized to one of three groups; usual care, basic intervention or extended intervention. The usual care received the normal care following the Danish standard procedure. The basic intervention had a medication review by a clinical pharmacist during admission. The extended interventions group was similar to the basic intervention group plus follow-up with the patient, the general practitioner and if relevant the nursing home and pharmacy one week and six month after discharge by interview with the clinical pharmacist.

Eligibility Criteria

Inclusion Criteria

  • Usual medicine of five drugs or above
  • Speak and understand Danish
  • Admitted via the Acute Medicine Admission Ward
  • Are able to give informed consent

Exclusion Criteria

  • Patients included in a similar study
  • Declared terminal
  • Suicidal
  • In custody
  • Isolated at the hospital
  • Im- and/or expressive aphasia
  • Severe dementia
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03079375). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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