Phase 4
Completed N=24
Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine
Anesthesia, Local
Source: ClinicalTrials.gov NCT03127943 ↗
Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Feb 2019
Primary outcomePrimary: Mean Time to Pulpal Response After Mandibular Molar Anesthesia — 100; 106 minutes
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Assess the clinical impact of Buffered 1% lidocaine with epinephrine as compared to the Non-buffered 1% lidocaine with epinephrine in dental and oral surgical procedures.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Time to Pulpal Response After Mandibular Molar Anesthesia |
100; 106 | — |
| PRIMARY Mean Time to Pulpal Response After Mandibular Canine Anesthesia |
81.3; 97.5 | — |
Eligibility Criteria
Inclusion Criteria
Age 18-30 years American Society Anesthesiologists I,II
Exclusion Criteria
Allergy to lidocaine class of anesthetic drugs Local anesthetic drug use in past week Current symptoms in teeth or oral mucosa
Data sourced from ClinicalTrials.gov (NCT03127943). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.